My definition of Mad Science:

1. It must be based on actual technology, vs. pseudo science.
2. It must be provocative, causing an initial reaction of horror or revulsion.
3. The horror or revulsion must be based on the concept rather than being simply disgusting.
4. It must have an artistic element, vs. being just science.

An April IEEE Spectrum story covers a work that wins on all counts: Dr. Hirotaka Osawa’s Wearable Eyes, designed to let you look like you care when you are phoning it in or even asleep!